Identification of a novel HLA-B*15 variant allele, HLA-B*15:276, in an umbilical cord blood donor

Tissue Antigens. 2014 Jun;83(6):428-9. doi: 10.1111/tan.12338. Epub 2014 Mar 20.

Abstract

A newly identified allele, named HLA B*15:276, differs from B*15:01:01:01 by the single nucleotide substitution 511T-C at codon 147 (Trp → Arg) in exon 3.

Keywords: B*15:276; HLA-B; novel allele; sequence-based typing; umbilical cord blood.

MeSH terms

  • Base Sequence
  • Exons / genetics
  • Genes, MHC Class I*
  • HLA-B Antigens / genetics*
  • Humans
  • Infant, Newborn
  • Italy
  • Living Donors
  • Molecular Sequence Data
  • Polymorphism, Single Nucleotide
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

Substances

  • HLA-B Antigens

Associated data

  • GENBANK/KC511054