Prevalence of radiographic osteoarthritis of the knee and its relationship to self-reported pain

PLoS One. 2014 Apr 10;9(4):e94563. doi: 10.1371/journal.pone.0094563. eCollection 2014.

Abstract

Background and aim: Osteoarthritis (OA) of the knee is one of the most common skeletal disorders, yet little data are available in Asian populations. We sought to assess the prevalence and pattern of radiographic OA of the knee, and its relationship to self-reported pain in a Vietnamese population.

Methods: The study was based on a sample of 170 men and 488 women aged ≥40 years who were randomly sampled from the Ho Chi Minh City (Vietnam). Radiographs of the knee were graded from 0 to 4 according to the Kellgren and Lawrence scale. Osteoarthritis was defined as being present in a knee if radiographic grades of 2 or higher were detected. Knee pain and symptoms were ascertained by direct interview using a structured questionnaire.

Results: The point prevalence of radiographic OA of the knee was 34.2%, with women having higher rate than men (35.3% vs 31.2%). The prevalence of knee OA increased with advancing age: 8% among those aged 40-49 years, 30% in those aged 50-59 years, and 61.1% in those aged ≥60 years. Greater BMI was associated with higher risk of knee OA. Self-reported knee pain was found in 35% of men and 62% of women. There was a statistically significant association between self-reported knee pain and knee OA (prevalence ratio 3.1; 95% CI 2.0 to 4.6).

Conclusions: These data indicate that approximately a third of Vietnamese men and women have radiographic OA in the knee, and that self-reported knee pain may be used as an indicator of knee osteoarthritis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Body Mass Index
  • Cross-Sectional Studies
  • Female
  • Humans
  • Knee Joint / diagnostic imaging
  • Knee Joint / pathology*
  • Male
  • Middle Aged
  • Osteoarthritis, Knee / complications
  • Osteoarthritis, Knee / diagnostic imaging
  • Osteoarthritis, Knee / epidemiology*
  • Osteoarthritis, Knee / pathology
  • Pain / complications
  • Pain / diagnostic imaging
  • Pain / epidemiology*
  • Pain / pathology
  • Prevalence
  • Radiography
  • Self Report
  • Sex Factors
  • Surveys and Questionnaires
  • Vietnam

Grants and funding

The study was partially supported by a grant from the Department of Science and Technology, Ho Chi Minh City, and a grant from the University Commission for Development (CUD) program, Belgium. Professor T.V. Nguyen is supported by a fellowship of the Australian National Health and Medical Research Council. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.