Autophagy: close contact keeps out the uninvited

Curr Biol. 2014 Jun 16;24(12):R560-R562. doi: 10.1016/j.cub.2014.05.013.

Abstract

In selective autophagy, autophagosomes sequester specific targets to be degraded in lysosomes/vacuoles. A new study now provides critical insights into the mechanism by which the autophagosomal membrane closely sticks to the target to avoid incorporating material that should not be degraded.

Publication types

  • Comment

MeSH terms

  • Autophagy*
  • Cell Membrane / metabolism*
  • Microtubule-Associated Proteins / metabolism*
  • Receptors, Cell Surface / metabolism*
  • Saccharomyces cerevisiae Proteins / metabolism*
  • Vesicular Transport Proteins / metabolism*

Substances

  • Microtubule-Associated Proteins
  • Receptors, Cell Surface
  • Saccharomyces cerevisiae Proteins
  • Vesicular Transport Proteins