Ocular findings in syndromic gingival fibromatosis: a case study and electronic microscopic investigation of lens

Ye-Lei Tang; Xing-Chao Shentu; Su-Juan Zhao; Xia-Jing Tang; Long He; Fei-Yun Ping

doi:10.3980/j.issn.2222-3959.2014.03.32

Ocular findings in syndromic gingival fibromatosis: a case study and electronic microscopic investigation of lens

Int J Ophthalmol. 2014 Jun 18;7(3):574-6. doi: 10.3980/j.issn.2222-3959.2014.03.32. eCollection 2014.

Authors

Ye-Lei Tang¹, Xing-Chao Shentu², Su-Juan Zhao², Xia-Jing Tang², Long He³, Fei-Yun Ping³

Affiliations

¹ Department of Neurology, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
² Eye Center, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
³ Department of Stomatology, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.

PMID: 24967210
PMCID: PMC4067678
DOI: 10.3980/j.issn.2222-3959.2014.03.32

Abstract

We report a case of syndromic gingival fibromatosis with notable ocular lesions, bilateral congenital cataracts, esotropia, and high myopia of a 21-year-old male patient from China. The patient was diagnosed with gingival fibromatosis based on his massive gingival overgrowth and histological findings that were consistent with gingival fibromatosis through a gingival biopsy. Lens opacity features were presented and phacoemulsificaion with intraocular lens(IOL) implantation was performed to manage the cataracts in both eyes. Transmission electronic microscopy was used to investigate the ultrastructure of the removed lens tissue. We also review the literature on gingival fibromatosis and briefly summarize the ocular manifestations of this rare disease.

Keywords: congenital cataract; syndrome; transmission electron microscopy gingival fibromatosis.