Abstract
This review deals with the chronic lymphoproliferative disease of large granular lymphocytes endowed with T and natural killer cell characteristics. The disease is sufficiently characterized to allow its distinction from other lymphoproliferative disorders of the T cell type. The heterogeneous clinical course and laboratory findings illustrate the complexity of the interaction between proliferating large granular lymphocytes and other haematopoietic cells.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Antigens, Differentiation, T-Lymphocyte / analysis
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Arthritis, Rheumatoid / complications
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Autoimmune Diseases / etiology
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B-Lymphocytes / pathology
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Diagnosis, Differential
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Lymphoproliferative Disorders* / diagnosis
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Lymphoproliferative Disorders* / genetics
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Lymphoproliferative Disorders* / immunology
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Lymphoproliferative Disorders* / pathology
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Pancytopenia / etiology
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T-Lymphocytes / classification
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T-Lymphocytes / pathology*
Substances
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Antigens, Differentiation, T-Lymphocyte