1 Dept of Medicine, University of British Columbia, Vancouver, BC, Canada.
2 Dept of Respiratory Medicine, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia.
3 Dept of Medicine, University of California San Francisco, San Francisco, CA, USA.
4 Academic Unit of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, UK Southampton NIHR Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK L.Richeldi@soton.ac.uk.