The protein-sparing modified fast for obese patients with type 2 diabetes: what to expect

Julia Chang; Sangeeta R Kashyap

doi:10.3949/ccjm.81a.13128

The protein-sparing modified fast for obese patients with type 2 diabetes: what to expect

Cleve Clin J Med. 2014 Sep;81(9):557-65. doi: 10.3949/ccjm.81a.13128.

Authors

Julia Chang¹, Sangeeta R Kashyap²

Affiliations

¹ Case Western Reserve University School of Medicine, Cleveland, OH.
² Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic; Associate Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH kashyas@ccf.org.

PMID: 25183847
DOI: 10.3949/ccjm.81a.13128

Abstract

The protein-sparing modified fast (PSMF) is a very-low-calorie diet containing mostly protein and little carbohydrate. This article reviews the principles of the PSMF and its potential benefits in terms of weight loss, glycemic control, insulin resistance, cardiovascular risk factors, and related complications for patients with type 2 diabetes.

Publication types

Review

MeSH terms

Blood Glucose / metabolism
Body Mass Index
Caloric Restriction*
Diabetes Mellitus, Type 2 / complications*
Dietary Carbohydrates / administration & dosage
Dietary Fats / administration & dosage
Dietary Proteins / administration & dosage*
Glycated Hemoglobin / metabolism
Humans
Insulin Resistance
Obesity / complications
Obesity / diet therapy*
Weight Gain
Weight Loss

Substances

Blood Glucose
Dietary Carbohydrates
Dietary Fats
Dietary Proteins
Glycated Hemoglobin A
hemoglobin A1c protein, human