The Canadian systemic sclerosis oral health study II: the relationship between oral and global health-related quality of life in systemic sclerosis

Murray Baron; Marie Hudson; Solène Tatibouet; Russell Steele; Ernest Lo; Sabrina Gravel; Geneviève Gyger; Tarek El Sayegh; Janet Pope; Audrey Fontaine; Ariel Masetto; Debora Matthews; Evelyn Sutton; Norman Thie; Niall Jones; Maria Copete; Dean Kolbinson; Janet Markland; Getulio Nogueira-Filho; David Robinson; Mervyn Gornitsky

doi:10.1093/rheumatology/keu396

The Canadian systemic sclerosis oral health study II: the relationship between oral and global health-related quality of life in systemic sclerosis

Rheumatology (Oxford). 2015 Apr;54(4):692-6. doi: 10.1093/rheumatology/keu396. Epub 2014 Oct 6.

Authors

Murray Baron¹, Marie Hudson¹, Solène Tatibouet², Russell Steele¹, Ernest Lo², Sabrina Gravel², Geneviève Gyger¹, Tarek El Sayegh², Janet Pope², Audrey Fontaine², Ariel Masetto², Debora Matthews², Evelyn Sutton², Norman Thie², Niall Jones², Maria Copete², Dean Kolbinson², Janet Markland², Getulio Nogueira-Filho², David Robinson², Mervyn Gornitsky²

Affiliations

¹ Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, McGill University, Montreal, QC, Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital, Montreal, Department of Mathematics and Statistics, Dentistry, Division of Rheumatology, Department of Medicine, University of Western Ontario, London, ON, Dentistry, Clinique Dentaire Ayotte et associées, Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Division of Periodontics and Oro-facial Pain, Faculty of Dentistry, Dalhousie University, Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, TMD/Orofacial Pain Graduate Program, School of Dentistry, Department of Medicine, University of Alberta, Edmonton, AB, College of Dentistry, Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Department of Periodontology, Faculty of Dentistry, Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, MB and Department of Dentistry, SMBD Jewish General Hospital, McGill University, Montreal, QC, Canada. Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, McGill University, Montreal, QC, Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital, Montreal, Department of Mathematics and Statistics, Dentistry, Division of Rheumatology, Department of Medicine, University of Western Ontario, London, ON, Dentistry, Clinique Dentaire Ayotte et associées, Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Division of Periodontics and Oro-facial Pain, Faculty of Dentistry, Dalhousie University, Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, TMD/Orofacial Pain Graduate Program, School of Dentistry, Department of Medicine, University of Alberta, Edmonton, AB, College of Dentistry, Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Department of Period
² Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, McGill University, Montreal, QC, Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital, Montreal, Department of Mathematics and Statistics, Dentistry, Division of Rheumatology, Department of Medicine, University of Western Ontario, London, ON, Dentistry, Clinique Dentaire Ayotte et associées, Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Division of Periodontics and Oro-facial Pain, Faculty of Dentistry, Dalhousie University, Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, TMD/Orofacial Pain Graduate Program, School of Dentistry, Department of Medicine, University of Alberta, Edmonton, AB, College of Dentistry, Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Department of Periodontology, Faculty of Dentistry, Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, MB and Department of Dentistry, SMBD Jewish General Hospital, McGill University, Montreal, QC, Canada.

Abstract

Objective: Both oral and global health-related quality of life (HRQoL) are markedly impaired in SSc. In this study we aimed to determine the degree of association between oral HRQoL and global HRQoL in SSc.

Methods: Subjects were recruited from the Canadian Scleroderma Research Group registry. Global HRQoL was measured using the Medical Outcomes Trust 36-item Short Form Health Survey (SF-36) and oral HRQoL with the Oral Health Impact Profile (OHIP). The Medsger Disease Severity Score was used to determine organ involvement. Multivariate regression models determined the independent association of the OHIP with the SF-36 after adjusting for confounders.

Results: This study included 156 SSc subjects. The majority (90%) were women, with a mean age of 56 years, mean disease duration 13.8 years (s.d. 8.5) and 29% of the subjects had dcSSc. Mean total OHIP score was 40.8 (s.d. 32.4). Mean SF-36 mental component summary (MCS) score was 49.7 (s.d. 11.1) and physical component summary (PCS) score was 37.0 (s.d. 10.7). In adjusted analyses, the total OHIP score was significantly associated with the SF-36 MCS and PCS, accounting for 9.7% and 5.6% of their respective variances. Measures of disease severity were not related to OHIP score.

Conclusion: Oral HRQoL in SSc is independently associated with global HRQoL. Oral HRQoL, however, is not related to physician-assessed disease severity. This suggests that physicians may be disregarding issues related to oral health. HRQoL is an additional dimension of HRQoL not captured by generic instruments such as the SF-36.

Keywords: oral health; oral hygiene; oral pathology; quality of life; questionnaires; systemic scleroderma.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Canada
Cross-Sectional Studies
Female
Health Status*
Humans
Linear Models
Male
Middle Aged
Oral Health*
Quality of Life*
Scleroderma, Systemic / physiopathology*
Severity of Illness Index
Surveys and Questionnaires

Grants and funding

Canadian Institutes of Health Research/Canada