Organic transdermal iontophoresis patch with built-in biofuel cell

Yudai Ogawa; Koichiro Kato; Takeo Miyake; Kuniaki Nagamine; Takuya Ofuji; Syuhei Yoshino; Matsuhiko Nishizawa

doi:10.1002/adhm.201400457

Organic transdermal iontophoresis patch with built-in biofuel cell

Adv Healthc Mater. 2015 Mar 11;4(4):506-10. doi: 10.1002/adhm.201400457. Epub 2014 Nov 17.

Authors

Yudai Ogawa¹, Koichiro Kato, Takeo Miyake, Kuniaki Nagamine, Takuya Ofuji, Syuhei Yoshino, Matsuhiko Nishizawa

Affiliation

¹ Department of Bioengineering and Robotics, Tohoku University, 6-6-1 Aramaki Aoba, Sendai, 980-8579, Japan.

PMID: 25402232
DOI: 10.1002/adhm.201400457

Abstract

A completely organic iontophoresis patch is reported. A built-in biofuel cell is mounted on the patch that generates transdermal iontophoretic administration of compounds into the skin. The amplitude of transdermal current is tuned by integrating a conducting polymer-based stretchable resistor of predetermined resistance.

Keywords: biofuel cells; drug delivery; iontophoresis; skin patch.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Administration, Cutaneous
Animals
Bioelectric Energy Sources*
Bridged Bicyclo Compounds, Heterocyclic / chemistry
Electric Impedance
Humans
Iontophoresis*
Male
Polymers / chemistry
Polyurethanes / chemistry
Rhodamines / chemistry
Sus scrofa
Transdermal Patch*

Substances

Bridged Bicyclo Compounds, Heterocyclic
Polymers
Polyurethanes
Rhodamines
poly(3,4-ethylene dioxythiophene)
rhodamine B