Genetically encoded Ca(2+) indicators; expanded affinity range, color hue and compatibility with optogenetics

Front Mol Neurosci. 2014 Nov 25:7:90. doi: 10.3389/fnmol.2014.00090. eCollection 2014.

¹ Department of Biomolecular Science and Engineering, The Institute of Scientific and Industrial Research, Osaka University Osaka, Japan ; PRESTO, Japan Science and Technology Agency Tokyo, Japan.
² Division for Bioimaging, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima, Japan.
³ Department of Systems Neuroscience, Centre for Brain Integration Research, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Bunkyo-ku, Tokyo, Japan.
⁴ Department of Biomolecular Science and Engineering, The Institute of Scientific and Industrial Research, Osaka University Osaka, Japan.

No abstract available

Keywords: Ca2+ imaging; FRET; bioluminescence; fluorescence; genetically encoded calcium ion indicator.