Relation between immunocytochemical estimation of oestrogen receptor in elderly patients with primary breast cancer and response to tamoxifen

D J Gaskell; R A Hawkins; K Sangsterl; U Chetty; A P Forrest

doi:10.1016/s0140-6736(89)92445-8

Relation between immunocytochemical estimation of oestrogen receptor in elderly patients with primary breast cancer and response to tamoxifen

Lancet. 1989 May 13;1(8646):1044-6. doi: 10.1016/s0140-6736(89)92445-8.

Authors

D J Gaskell¹, R A Hawkins, K Sangsterl, U Chetty, A P Forrest

Affiliation

¹ University Department of Surgery, Royal Infirmary of Edinburgh.

PMID: 2566000
DOI: 10.1016/s0140-6736(89)92445-8

Abstract

The relation between oestrogen receptor status of primary breast cancer as determined immuncytochemically on fine-needle aspirates and the response to tamoxifen therapy has been assessed in 52 patients. The proportion of cells staining correlated well with the likelihood of response, which emphasises the importance of tumour heterogeneity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Biopsy, Needle
Breast / pathology
Breast Neoplasms / analysis*
Breast Neoplasms / drug therapy
Breast Neoplasms / pathology
Carcinoma / analysis*
Carcinoma / drug therapy
Carcinoma / pathology
Evaluation Studies as Topic
Female
Follow-Up Studies
Humans
Immunohistochemistry
Receptors, Estrogen / analysis*
Retrospective Studies
Tamoxifen / therapeutic use*

Substances

Receptors, Estrogen
Tamoxifen