Maternal glucose during pregnancy and after delivery in women with gestational diabetes mellitus on overweight status of their children

Biomed Res Int. 2015:2015:543038. doi: 10.1155/2015/543038. Epub 2015 Feb 23.

Abstract

Objective: To examine the association of maternal glycemia during pregnancy and after delivery with anthropometry in the offspring of mothers with gestational diabetes mellitus (GDM).

Methods: A total of 1,263 GDM mothers and their children finished the health survey at 1-5 years after delivery.

Results: Offspring of GDM mothers who were diagnosed with diabetes during pregnancy had higher prevalence of overweight, higher mean weight for height Z scores, and higher mean BMI for age Z scores at 1-5 years old than the offspring of GDM mothers who were diagnosed with impaired glucose tolerance (IGT) during pregnancy. Offspring of GDM mothers who developed diabetes 1-5 years after delivery had higher mean values of Z scores for weight for height and BMI for age at 1-5 years old than the offspring of GDM mothers who had normal glucose or prediabetes after delivery.

Conclusions: Offspring of GDM mothers who were diagnosed with diabetes during pregnancy or after delivery had an increased risk of childhood overweight or weight gain at 1-5 years old compared with children of GDM mothers with IGT during pregnancy or with normal glucose or prediabetes after delivery.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose / metabolism*
  • Body Height
  • Body Mass Index
  • Body Weight
  • Child, Preschool
  • China / epidemiology
  • Delivery, Obstetric*
  • Diabetes, Gestational / blood*
  • Female
  • Humans
  • Male
  • Overweight / epidemiology
  • Overweight / etiology*
  • Pregnancy
  • Prevalence
  • Risk Factors

Substances

  • Blood Glucose