Different sites within the oropharynx harbour unique microbial communities. Co-evolution of microbes and host has resulted in complex interkingdom circuitries. Metabolic signalling is crucial to these processes, and novel microbial communication factors are progressively being discovered. Resolving interkingdom networks will lead to better understanding of oral health or disease aetiology.
Keywords: Biofilms; Candida albicans; Microbial communities; Porphyromonas; Quorum sensing; Streptococcus.
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