Abstract
A new casbane diterpenoid, referred to as pekinenin G, together with one cembrane diterpene and four known casbane diterpenoids were isolated from the roots of Euphorbia pekinensis. Their structures were elucidated on the basis of spectroscopic studies and comparison with related known compounds. The six compounds showed different cytotoxic activities against four human cancer cell lines.
Keywords:
Euphorbia pekinensis; casbane diterpenoid; cytotoxic activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry*
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Cell Line, Tumor / drug effects
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Diterpenes / chemistry*
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Diterpenes / isolation & purification
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Diterpenes / pharmacology
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Euphorbia / chemistry*
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Humans
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Molecular Structure
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Plant Roots / chemistry
Substances
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Antineoplastic Agents, Phytogenic
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Diterpenes
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pekinenin G
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cembrane