Genetics: dynamic cellular aging markers associated with major depression

Iiris Hovatta

doi:10.1016/j.cub.2015.03.036

Genetics: dynamic cellular aging markers associated with major depression

Curr Biol. 2015 May 18;25(10):R409-11. doi: 10.1016/j.cub.2015.03.036.

Author

Iiris Hovatta¹

Affiliation

¹ Department of Biosciences, University of Helsinki, Helsinki, Finland and Department of Health, National Institute for Health and Welfare, Helsinki, Finland. Electronic address: iiris.hovatta@helsinki.fi.

PMID: 25989078
DOI: 10.1016/j.cub.2015.03.036

Abstract

Psychiatric diseases are associated with an increased rate of somatic age-related illness. A new study sheds light on putative mediating cellular mechanisms by linking increased mitochondrial DNA copy number and decreased telomere length to childhood stress and major depression.

Publication types

Comment

MeSH terms

Animals
DNA, Mitochondrial / metabolism*
Depressive Disorder, Major / metabolism*
Female
Humans
Male
Stress, Psychological / metabolism*
Telomere Shortening*

Substances

DNA, Mitochondrial