[Methicillin-resistant staphylococcal enterocolitis developed after induction chemotherapy in a case of acute promyelocytic leukemia]

Rinsho Ketsueki. 1989 Aug;30(8):1319-20.
[Article in Japanese]

Abstract

A case of methicillin-resistant staphylococcal (MRSA) enterocolitis following combination chemotherapy for acute promyelocytic leukemia is presented. MRSA enterocolitis has characteristic clinical features of high fever, frequent vomiting and watery diarrhea, and its mortality rate is very high without a proper antibiotic therapy. When the patient with hematological malignancy has the above-mentioned clinical manifestations during antineoplastic chemotherapy, appropriate antibiotics for MRSA should be promptly begun before a bacteriological diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Cytarabine / administration & dosage
  • Cytarabine / analogs & derivatives
  • Daunorubicin / administration & dosage
  • Enterocolitis / etiology*
  • Humans
  • Leukemia, Promyelocytic, Acute / drug therapy*
  • Male
  • Mercaptopurine / administration & dosage
  • Methicillin / pharmacology*
  • Middle Aged
  • Penicillin Resistance
  • Prednisolone / administration & dosage
  • Remission Induction
  • Staphylococcal Infections*
  • Staphylococcus aureus / drug effects

Substances

  • Cytarabine
  • Prednisolone
  • Mercaptopurine
  • Methicillin
  • Daunorubicin

Supplementary concepts

  • BH-AC-DMP protocol