Abstract
In February 2015, a male patient from Eritrea with persistent abdominal pain and rectal bleeding was diagnosed with Schistosoma mansoni infection upon examination of a rectal biopsy. In May 2015, repeated stool microscopy identified S. mansoni infection in another Eritrean patient with abdominal pain and considerable eosinophilia (34%). Use of point-of-care circulating cathodic antigen (POC-CCA) tests on urine confirmed S. mansoni infection in both patients. Wider application of non-invasive POC-CCA urine tests will improve schistosomiasis diagnosis and clinical management in migrants.
MeSH terms
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Adolescent
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Animals
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Anthelmintics / therapeutic use
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Antigens, Helminth / urine*
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Biopsy
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Clinical Laboratory Techniques
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Eritrea
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Feces / parasitology
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Germany
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Glycoproteins
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Helminth Proteins
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Humans
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Male
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Point-of-Care Systems*
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Praziquantel / therapeutic use
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Rectal Diseases
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Schistosoma mansoni / immunology*
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Schistosoma mansoni / isolation & purification
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Schistosomiasis mansoni / diagnosis*
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Schistosomiasis mansoni / drug therapy
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Schistosomiasis mansoni / urine*
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Sensitivity and Specificity
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Transients and Migrants
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Travel*
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Treatment Outcome
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Young Adult
Substances
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Anthelmintics
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Antigens, Helminth
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CCA protein, Schistosoma mansoni
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Glycoproteins
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Helminth Proteins
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Praziquantel