An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference

Gerd A Blobel; David Bodine; Marjorie Brand; John Crispino; Marella F T R de Bruijn; David Nathan; Thalia Papayannopoulou; Catherine Porcher; John Strouboulis; Len Zon; Douglas R Higgs; George Stamatoyannopoulos; James Douglas Engel

doi:10.1016/j.exphem.2015.06.008

An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference

Exp Hematol. 2015 Oct;43(10):821-37. doi: 10.1016/j.exphem.2015.06.008. Epub 2015 Jul 2.

Authors

Affiliations

¹ Division of Hematology, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
² National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
³ Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
⁴ Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA.
⁵ MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital University of Oxford, Oxford, UK; BRC Blood Theme, NIHR Oxford Biomedical Centre, Oxford University Hospital, Oxford, UK.
⁶ Division of Hematology and Oncology, Boston Children's Hospital, Departments of Pediatrics and Medicine, Harvard Medical School, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
⁷ Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
⁸ Division of Molecular Oncology, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
⁹ Boston Children's Hospital/HHMI, Boston, MA, USA.
¹⁰ Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: engel@umich.edu.

Abstract

Every 2 years since 1978, an international group of scientists, physicians, and other researchers meet to discuss the latest developments in the underlying etiology, mechanisms of action, and developmental acquisition of cellular and systemic defects exhibited and elicited by the most common inherited human disorders, the hemoglobinopathies. The 19th Hemoglobin Switching Conference, held in September 2014 at St. John's College in Oxford, once again exceeded all expectations by describing cutting edge research in cellular, molecular, developmental, and genomic advances focused on these diseases. The conference comprised about 60 short talks over 3 days by leading investigators in the field. This meeting report describes the highlights of the conference.

Publication types

Review

MeSH terms

Congresses as Topic
Hemoglobinopathies / genetics*
Hemoglobinopathies / metabolism*
Hemoglobinopathies / pathology
Hemoglobinopathies / therapy
Hemoglobins / genetics*
Hemoglobins / metabolism*
Humans

Substances

Hemoglobins

Abstract

Publication types

MeSH terms

Substances

Grants and funding