DNMT1 and Cancer: An Electrifying Link

Nicole N Nuñez; Amelia H Manlove; Sheila S David

doi:10.1016/j.chembiol.2015.07.004

DNMT1 and Cancer: An Electrifying Link

Chem Biol. 2015 Jul 23;22(7):810-1. doi: 10.1016/j.chembiol.2015.07.004.

Authors

Nicole N Nuñez¹, Amelia H Manlove¹, Sheila S David²

Affiliations

¹ Department of Chemistry, University of California, Davis, One Shields Ave, Davis, CA 95616, USA.
² Department of Chemistry, University of California, Davis, One Shields Ave, Davis, CA 95616, USA. Electronic address: ssdavid@ucdavis.edu.

PMID: 26207295
DOI: 10.1016/j.chembiol.2015.07.004

Abstract

Aberrant epigenetic methylation is linked to the onset and progression of cancer. In this issue of Chemistry & Biology, Furst and Barton (2015) describe a sensitive electrochemical assay that can detect hyperactive epigenetic methylation in tumor tissue.

Publication types

Comment

MeSH terms

Colorectal Neoplasms / enzymology*
DNA (Cytosine-5-)-Methyltransferases / metabolism*
Humans

Substances

DNA (Cytosine-5-)-Methyltransferases