p53 activity contributes to defective interfollicular epidermal differentiation in hyperproliferative murine skin

Br J Dermatol. 2016 Jan;174(1):204-8. doi: 10.1111/bjd.14048. Epub 2015 Nov 20.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation / physiology
  • Cell Proliferation / physiology*
  • Epidermis / pathology*
  • Gene Knockout Techniques
  • Keratin-6 / metabolism
  • Keratinocytes / pathology
  • Keratinocytes / physiology
  • Mice
  • Mice, Inbred Strains
  • PPAR gamma / metabolism
  • PPAR-beta / metabolism
  • Signal Transduction / physiology
  • Skin Diseases / pathology*
  • Tretinoin / antagonists & inhibitors
  • Tretinoin / physiology
  • Tumor Suppressor Protein p53 / deficiency
  • Tumor Suppressor Protein p53 / physiology*
  • Up-Regulation

Substances

  • Keratin-6
  • PPAR gamma
  • PPAR-beta
  • Tumor Suppressor Protein p53
  • Tretinoin