Sex differences in predictors of ischemic stroke: current perspectives

Vasc Health Risk Manag. 2015 Jul 27:11:427-36. doi: 10.2147/VHRM.S65886. eCollection 2015.

Abstract

Globally, stroke is a significant public health concern affecting more than 33 million individuals. Of growing importance are the differences between males and females in the predictors and overall risk of stroke. Given that women have a higher lifetime risk for stoke and account for more than half of all stroke deaths, sex-specific stroke risk factors merit investigation and may help target public health interventions. This review aims to discuss the current body of knowledge regarding sex-specific predictors of ischemic stroke including both modifiable and non-modifiable risk factors, as well as specific pathologies known to increase stroke risk.

Keywords: cerebral stroke; risk factors; sex; thrombosis.

Publication types

  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Behavioral Risk Factor Surveillance System
  • Brain Ischemia / epidemiology*
  • Cardiovascular Diseases / complications
  • Cardiovascular Diseases / epidemiology
  • Diabetes Complications
  • Female
  • Humans
  • Hypertension / complications
  • Hypertension / epidemiology
  • Indians, North American / statistics & numerical data
  • Male
  • Risk Factors
  • Sex Factors
  • Smoking / adverse effects
  • Smoking / epidemiology
  • Stroke / epidemiology*
  • United States / epidemiology