Determinants of adherence to treatment in hypertensive patients of African descent and the role of culturally appropriate education

PLoS One. 2015 Aug 12;10(8):e0133560. doi: 10.1371/journal.pone.0133560. eCollection 2015.

Abstract

Background: In Western countries, better knowledge about patient-related determinants of treatment adherence (medication and lifestyle) is needed to improve treatment adherence and outcomes among hypertensive ethnic minority patients of African descent.

Objective: To identify patient-related determinants of adherence to lifestyle and medication recommendations among hypertensive African Surinamese and Ghanaian patients with suboptimal treatment results (SBP≥140) living in the Netherlands and how culturally appropriate hypertension education (CAHE) influenced those determinants.

Methods: This study analysed data of 139 patients who participated in the CAHE trial. Univariate logistic regression analysis was used to measure the association between patient-related determinants (medication self-efficacy, beliefs about medication and hypertension, social support, and satisfaction with care) and treatment adherence. We also tested whether CAHE influenced the determinants.

Results: Medication self-efficacy and social support were associated with medication adherence at baseline. At six months, more medication self-efficacy and fewer concerns about medication use were associated with improved medication adherence. Self-efficacy was also associated with adherence to lifestyle recommendations at baseline. CAHE influenced patients' illness perceptions by creating more understanding of hypertension, its chronic character, and more concerns about the associated risks.

Conclusion: In this high-risk population, health care providers can support medication adherence by paying attention to patients' medication self-efficacy, the concerns they may have about medication use and patients' perceptions on hypertension. The CAHE intervention improved patients' perception on hypertension.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antihypertensive Agents / therapeutic use*
  • Black People / psychology*
  • Culture
  • Female
  • Health Knowledge, Attitudes, Practice / ethnology*
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / ethnology
  • Hypertension / physiopathology
  • Hypertension / psychology*
  • Male
  • Medication Adherence / ethnology
  • Medication Adherence / psychology*
  • Middle Aged
  • Netherlands
  • Patient Education as Topic
  • Patient Satisfaction / ethnology
  • Self Efficacy
  • Treatment Outcome

Substances

  • Antihypertensive Agents

Grants and funding

This study was funded by ZonMw, the Netherlands organisation for health research and development (grants no. 122000008 and 12010095425), http://www.zonmw.nl/en/. The study sponsor carried out annual reviews of the study's progress but had no active role in the study design, data collection, analysis and reporting, nor in the preparation of this manuscript.