Antibiotics in cell culture: friend or foe? Suppression of keratinocyte growth and differentiation in monolayer cultures and 3D skin models

Exp Dermatol. 2015 Dec;24(12):964-5. doi: 10.1111/exd.12834. Epub 2015 Oct 6.

Authors

Uffe H Nygaard^{1

2}, Hanna Niehues³, Gijs Rikken³, Diana Rodijk-Olthuis³, Joost Schalkwijk³, Ellen H van den Bogaard³

Affiliations

¹ Department of Dermatology and Venereology, Aarhus University Hospital, Aarhus, Denmark.
² Department of Clinical medicine, Aarhus University, Aarhus C, Denmark.
³ Department of Dermatology, Radboud Institute for Molecular Life Sciences, Radboud university medical centre, Nijmegen, The Netherlands.

PMID: 26287649
DOI: 10.1111/exd.12834

No abstract available

Keywords: gentamycin; keratinocytes; penicillin; proliferation; streptomycin.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / administration & dosage*
Anti-Bacterial Agents / toxicity
Cell Culture Techniques / methods*
Cell Differentiation / drug effects
Cell Proliferation / drug effects
Culture Media / adverse effects
Culture Media / chemistry
Epidermal Cells
Epidermis / drug effects
Epidermis / growth & development
Humans
Imaging, Three-Dimensional
Keratinocytes / cytology*
Keratinocytes / drug effects*
Models, Biological
Skin / cytology*
Skin / drug effects*
Skin / growth & development

Substances

Anti-Bacterial Agents
Culture Media