Allogeneic Transplantation for Unfavorable-Risk Acute Myeloid Leukemia

Abstract

Acute myeloid leukemia (AML) is a complex, heterogeneous disorder that can have devastating effects. Although control of AML can be attained with various induction regimens, long-term cure is much more difficult to maintain. This is understated in patients with unfavorable-risk AML, who are usually older and have prior myeloid and/or therapy-related disease and more challenges in curing this disease.

Keywords: Acute myeloid leukemia; Allogeneic hematopoietic cell transplantation; Consolidation therapy; Maintenance therapy; Unfavorable risk.