IL-1 as a target in inflammation

Endocr Metab Immune Disord Drug Targets. 2015;15(3):206-11.

Abstract

Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / administration & dosage*
  • Drug Delivery Systems / methods*
  • Humans
  • Inflammation / drug therapy
  • Inflammation / metabolism
  • Inflammation Mediators / antagonists & inhibitors
  • Inflammation Mediators / metabolism*
  • Interleukin-1 / antagonists & inhibitors
  • Interleukin-1 / metabolism*

Substances

  • Anti-Inflammatory Agents
  • Inflammation Mediators
  • Interleukin-1