Activation of Mg(2+)-dependent DNAzymes based on AP site-containing triplex for specific melamine recognition

Analyst. 2015 Nov 21;140(22):7508-12. doi: 10.1039/c5an01515d.

Abstract

Based on melamine binding-triggered triplex formation and subsequent activation of Mg(2+)-dependent DNAzymes, a novel strategy for DNAzyme regulation was proposed and developed for melamine recognition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Biosensing Techniques
  • Cations, Divalent / metabolism
  • DNA, Catalytic / chemistry
  • DNA, Catalytic / metabolism*
  • Magnesium / metabolism*
  • Spectrometry, Fluorescence
  • Triazines / analysis
  • Triazines / metabolism*

Substances

  • Cations, Divalent
  • DNA, Catalytic
  • Triazines
  • Magnesium
  • melamine