Clinical Approach to Diffuse Blisters

Tarannum Jaleel; Young Kwak; Naveed Sami

doi:10.1016/j.mcna.2015.07.009

Clinical Approach to Diffuse Blisters

Med Clin North Am. 2015 Nov;99(6):1243-67, xii. doi: 10.1016/j.mcna.2015.07.009.

Authors

Tarannum Jaleel¹, Young Kwak¹, Naveed Sami²

Affiliations

¹ Department of Dermatology, University of Alabama at Birmingham, 1520 3rd Avenue South, EFH 414, Birmingham, AL 35294-0009, USA.
² Department of Dermatology, University of Alabama at Birmingham, 1520 3rd Avenue South, EFH 414, Birmingham, AL 35294-0009, USA. Electronic address: nsami@uab.edu.

PMID: 26476251
DOI: 10.1016/j.mcna.2015.07.009

Abstract

Some blistering eruptions are self-limited, but others are life threatening, and prompt diagnosis and management are critical. The clinical presentation of vesicles and bullae suggests a broad differential and this article (1) highlights some common diagnoses that may be encountered by primary care physicians and subspecialists; (2) provides a possible systematic diagnostic approach to such patients, including history, physical examination, and relevant work-up.

Keywords: Autoimmune bullous disorders; Blisters; Bullous drug eruptions; Diffuse blisters; Vesicles; Vesiculobullous.

Publication types

Review

MeSH terms

Biopsy, Needle
Diagnosis, Differential
Fluorescent Antibody Technique, Direct
Humans
Medical History Taking
Physical Examination
Skin Diseases, Vesiculobullous / diagnosis*
Skin Diseases, Vesiculobullous / etiology*
Skin Diseases, Vesiculobullous / therapy