SnapShot: antiviral restriction factors

Silvia F Kluge; Daniel Sauter; Frank Kirchhoff

doi:10.1016/j.cell.2015.10.019

SnapShot: antiviral restriction factors

Cell. 2015 Oct 22;163(3):774-774.e1. doi: 10.1016/j.cell.2015.10.019. Epub 2015 Oct 22.

Authors

Silvia F Kluge¹, Daniel Sauter¹, Frank Kirchhoff¹

Affiliation

¹ Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.

PMID: 26496613
DOI: 10.1016/j.cell.2015.10.019

Abstract

Restriction factors are cellular proteins that inhibit viruses at different steps of their replication cycle and represent an important first line of defense against viral pathogens. This SnapShot provides an overview of cell-intrinsic antiviral factors, describes their properties, and illustrates the striking variety of antiviral mechanisms as well the sophisticated viral countermeasures. To view this SnapShot, open or download the PDF.

MeSH terms

Animals
Cells / virology*
Host-Pathogen Interactions*
Humans
Intracellular Signaling Peptides and Proteins / metabolism
Virus Diseases / immunology
Virus Diseases / metabolism*
Viruses / metabolism

Substances

Intracellular Signaling Peptides and Proteins