Effects of goat milk-based formula on development in weaned rats

Meihong Xu; Liren Wei; Zhiyong Dai; Yanchun Zhang; Yong Li; Junbo Wang

doi:10.3402/fnr.v59.28610

Effects of goat milk-based formula on development in weaned rats

Food Nutr Res. 2015 Dec 8:59:28610. doi: 10.3402/fnr.v59.28610. eCollection 2015.

Authors

Meihong Xu^{1

2}, Liren Wei^{1

2}, Zhiyong Dai³, Yanchun Zhang³, Yong Li^{1

2}, Junbo Wang^{1

4}

Affiliations

¹ Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China.
² Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University, Beijing, China.
³ Ausntria Hyproca Dairy Group BV, Changsha, China.
⁴ Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, Peking University, Beijing, China; bmuwjbxy@bjmu.edu.cn.

Abstract

Objective: The aim of this article is to study the effect of goat milk-based formula (GMF) on development in weaned rats.

Methods: One hundred Sprague-Dawley rats were randomly divided into five groups: control, 20% cow milk-based formula (CMF), and 5%-GMF, 10%-GMF, and 20%-GMF groups.

Results: GMF did play an active role in accelerating body and femur length, but not body weight growth. Compared with the control, GMF had better cognitive, space, and locomotor activity. The level of IFN was increased in GMF groups, as well as the level of IL-2 and TNF was decreased in GMF groups.

Conclusion: These results indicate that GMF has an effect on development and immunity improvability in weaned rats.

Keywords: development; goat milk–based formula; immunity; infant formula.