Reconstruction of paediatric organ doses from axial CT scans performed in the 1990s - range of doses as input to uncertainty estimates

Eur Radiol. 2016 Sep;26(9):3026-33. doi: 10.1007/s00330-015-4157-6. Epub 2016 Jan 23.

Abstract

Objective: To assess the range of doses in paediatric CT scans conducted in the 1990s in Norway as input to an international epidemiology study: the EPI-CT study, http://epi-ct.iarc.fr/ .

Methods: National Cancer Institute dosimetry system for Computed Tomography (NCICT) program based on pre-calculated organ dose conversion coefficients was used to convert CT Dose Index to organ doses in paediatric CT in the 1990s. Protocols reported from local hospitals in a previous Norwegian CT survey were used as input, presuming these were used without optimization for paediatric patients.

Results: Large variations in doses between different scanner models and local scan parameter settings are demonstrated. Small children will receive a factor of 2-3 times higher doses compared with adults if the protocols are not optimized for them. For common CT examinations, the doses to the active bone marrow, breast tissue and brain may have exceeded 30 mGy, 60 mGy and 100 mGy respectively, for the youngest children in the 1990s.

Conclusions: The doses children received from non-optimised CT examinations during the 1990s are of such magnitude that they may provide statistically significant effects in the EPI-CT study, but probably do not reflect current practice.

Key points: • Some organ doses from paediatric CT in the 1990s may have exceeded 100 mGy. • Small children may have received doses 2-3 times higher compared with adults. • Different scanner models varied by a factor of 2-3 in dose to patients. • Different local scan parameter settings gave dose variations of a factor 2-3. • Modern CTs and age-adjusted protocols will give much lower paediatric doses.

Keywords: Dose–response relationship, radiation; Paediatrics; Radiation dosage; Radiologic health; Tomography scanners, X-ray computed.

MeSH terms

  • Adolescent
  • Adult
  • Bone Marrow / diagnostic imaging
  • Brain / diagnostic imaging
  • Breast / diagnostic imaging
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Models, Theoretical*
  • Norway
  • Pediatrics / statistics & numerical data*
  • Phantoms, Imaging*
  • Radiation Dosage*
  • Radiometry / methods
  • Tomography, X-Ray Computed / methods*
  • Tomography, X-Ray Computed / statistics & numerical data
  • Uncertainty*