Versatile Stimulation Back-End With Programmable Exponential Current Pulse Shapes for a Retinal Visual Prosthesis

IEEE Trans Neural Syst Rehabil Eng. 2016 Nov;24(11):1243-1253. doi: 10.1109/TNSRE.2016.2542112. Epub 2016 Mar 30.

Abstract

This paper reports on the design, implementation, and test of a stimulation back-end, for an implantable retinal prosthesis. In addition to traditional rectangular pulse shapes, the circuit features biphasic stimulation pulses with both rising and falling exponential shapes, whose time constants are digitally programmable. A class-B second generation current conveyor is used as a wide-swing, high-output-resistance stimulation current driver, delivering stimulation current pulses of up to ±96 μA to the target tissue. Duration of the generated current pulses is programmable within the range of 100 μs to 3 ms. Current-mode digital-to-analog converters (DACs) are used to program the amplitudes of the stimulation pulses. Fabricated using the IBM 130 nm process, the circuit consumes 1.5×1.5 mm2 of silicon area. According to the measurements, the DACs exhibit DNL and INL of 0.23 LSB and 0.364 LSB, respectively. Experimental results indicate that the stimuli generator meets expected requirements when connected to electrode-tissue impedance of as high as 25 k Ω. Maximum power consumption of the proposed design is 3.4 mW when delivering biphasic rectangular pulses to the target load. A charge pump block is in charge of the upconversion of the standard 1.2-V supply voltage to ±3.3V.

Publication types

  • Evaluation Study

MeSH terms

  • Electric Power Supplies*
  • Electric Stimulation Therapy / instrumentation*
  • Equipment Design
  • Equipment Failure Analysis
  • Signal Processing, Computer-Assisted / instrumentation*
  • Therapy, Computer-Assisted / instrumentation*
  • Visual Prosthesis*
  • Wireless Technology / instrumentation*