Kleine-Levin syndrome is a rare recurrent hypersomnia associated with symptoms of behavioral and cognitive impairment. This article reviews common presenting symptoms, differential diagnosis, diagnostic workup, and potential treatment options. Current updates on functional imaging studies and long-term neuropsychological studies are reviewed.
Keywords: Adolescent; Derealization; Hyperphagia; Hypersexuality; Hypersomnia; Kleine-Levin syndrome; Sleep disorder.