Extranodal Lymphoma of the Breast

Brandi T Nicholson; Rahat M Bhatti; Leonard Glassman

doi:10.1016/j.rcl.2016.03.005

Extranodal Lymphoma of the Breast

Radiol Clin North Am. 2016 Jul;54(4):711-26. doi: 10.1016/j.rcl.2016.03.005.

Authors

Brandi T Nicholson¹, Rahat M Bhatti², Leonard Glassman³

Affiliations

¹ Department of Radiology & Medical Imaging, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: bte6v@virginia.edu.
² Department of Pathology, University of Virginia, Charlottesville, VA 22908, USA.
³ Washington Radiology Associates PC, Washington, DC 20037, USA.

PMID: 27265604
DOI: 10.1016/j.rcl.2016.03.005

Abstract

Extranodal lymphoma represents fewer than 0.5% of all breast malignancies. Secondary involvement of the breast with lymphoma is more common than primary breast lymphoma. The most common primary breast lymphoma is B-cell lymphoma. The initial imaging study of choice for a woman with a new breast mass is a diagnostic mammogram. In younger women ultrasound is more commonly the first imaging modality performed. Diagnosis is made from image-guided or physical examination-directed needle biopsy. Treatment is different from that for breast cancer, in that surgery is not the mainstay. Patients with breast lymphoma are treated primarily with chemotherapy and radiation.

Keywords: B-cell lymphoma; Breast; Extranodal lymphoma; Primary breast lymphoma; Secondary breast lymphoma.

Publication types

Review

MeSH terms

Chemoradiotherapy / methods*
Diagnosis, Differential
Evidence-Based Medicine
Female
Humans
Lymphoma / diagnostic imaging*
Lymphoma / pathology
Lymphoma / therapy*
Mammography / methods*
Palpation / methods