UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016

D Creamer; S A Walsh; P Dziewulski; L S Exton; H Y Lee; J K G Dart; J Setterfield; C B Bunker; M R Ardern-Jones; K M T Watson; G A E Wong; M Philippidou; A Vercueil; R V Martin; G Williams; M Shah; D Brown; P Williams; M F Mohd Mustapa; C H Smith

doi:10.1016/j.bjps.2016.01.034

UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016

J Plast Reconstr Aesthet Surg. 2016 Jun;69(6):e119-e153. doi: 10.1016/j.bjps.2016.01.034.

Authors

D Creamer¹, S A Walsh², P Dziewulski³, L S Exton⁴, H Y Lee⁵, J K G Dart⁶, J Setterfield⁷, C B Bunker⁸, M R Ardern-Jones⁹, K M T Watson¹⁰, G A E Wong¹¹, M Philippidou¹², A Vercueil¹³, R V Martin³, G Williams¹⁴, M Shah¹⁵, D Brown¹⁶, P Williams², M F Mohd Mustapa⁴, C H Smith¹⁶

Affiliations

¹ Department of Dermatology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, UK. Electronic address: guidelines@bad.org.uk.
² Department of Dermatology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, UK.
³ St Andrews Centre for Plastic Surgery and Burns, Mid Essex Hospital Services NHS Trust, Chelmsford, CM1 7ET, UK.
⁴ British Association of Dermatologists, Willan House, 4 Fitzroy Square, London, W1T 5HQ, UK.
⁵ Dermatology Unit, Singapore General Hospital, Singapore.
⁶ Moorfields Eye Hospital, 162 City Road, London, EC1V 2PD, UK.
⁷ Mucosa and Salivary Biology, Dental Institute, King's College London, Guy's Campus, Great Maze Pond, London, SE1 9RT, UK.
⁸ University College Hospital, London, NW1 2BU, UK.
⁹ Clinical Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.
¹⁰ Department of Dermatology, Orpington Hospital, Orpington, Kent, BR6 9JU, UK.
¹¹ Department of Dermatology, University Hospital of South Manchester NHS Foundation Trust, Manchester, M23 9LT, UK.
¹² Department of Histopathology, King's College Hospital NHS Foundation Trust, London, SE5 9RS, UK.
¹³ Intensive Care Medicine, King's College Hospital NHS Foundation Trust, London, SE5 9RS, UK.
¹⁴ Late of the Burns Centre, Chelsea and Westminster NHS Foundation Trust, London, SW10 9NH, UK.
¹⁵ Department of Burns and Plastic Surgery, University Hospitals of South Manchester, Southmoor Road, Wythenshawe, Manchester, M23 9LT, UK.
¹⁶ St John's Institute of Dermatology, Guy's and St Thomas NHS Foundation Trust, London, SE1 9RT, UK.

PMID: 27287213
DOI: 10.1016/j.bjps.2016.01.034

Abstract

The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap in adults during the acute phase of the disease. The document aims to.

Keywords: Drug hypersensitivity; Guidelines; Management; Stevens–Johnson syndrome; Toxic epidermal necrolysis.

MeSH terms

Adult
Diagnosis, Differential
Disease Management*
Evidence-Based Practice
Humans
Patient Acuity
Practice Guidelines as Topic*
Skin / pathology
Stevens-Johnson Syndrome* / diagnosis
Stevens-Johnson Syndrome* / physiopathology
Stevens-Johnson Syndrome* / therapy
United Kingdom