Schwannoma Showing Avid Uptake on 68Ga-PSMA-HBED-CC PET/CT

Clin Nucl Med. 2016 Sep;41(9):703-4. doi: 10.1097/RLU.0000000000001281.

Abstract

Ga prostate-specific membrane antigen (PSMA) PET/CT is a relatively new and highly sensitive imaging modality used in staging metastatic prostate cancer. We report a case of a 65-year-old man with newly diagnosed prostate carcinoma who had a PSMA PET/CT scan for staging of his disease. A PSMA-avid right pelvic mass was identified anterior to the sacrum. Surgical removal and histopathological examination of this lesion revealed the diagnosis of schwannoma. It is important to be aware that schwannoma may also show avid uptake on PSMA PET/CT scan and may potentially lead to an incorrect diagnosis of metastatic prostate carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, Surface / metabolism
  • Diagnosis, Differential
  • Edetic Acid / analogs & derivatives
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Glutamate Carboxypeptidase II / metabolism
  • Humans
  • Male
  • Neurilemmoma / diagnostic imaging*
  • Oligopeptides
  • Organometallic Compounds
  • Positron Emission Tomography Computed Tomography* / methods
  • Prostatic Neoplasms / diagnostic imaging*

Substances

  • Antigens, Surface
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Oligopeptides
  • Organometallic Compounds
  • gallium 68 PSMA-11
  • Edetic Acid
  • FOLH1 protein, human
  • Glutamate Carboxypeptidase II