Minimally Invasive vs. Open Hepatectomy: a Comparative Analysis of the National Surgical Quality Improvement Program Database

J Gastrointest Surg. 2016 Sep;20(9):1608-17. doi: 10.1007/s11605-016-3202-3. Epub 2016 Jul 13.

Abstract

Background: While minimally invasive surgery (MIS) to treat liver tumors has increased, data on perioperative outcomes of MIS relative to open liver resection (O-LR) are lacking. We sought to compare short-term outcomes among patients undergoing MIS vs. O-LR in a nationally representative database.

Methods: The National Surgical Quality Improvement Program database was used to identify patients undergoing hepatectomy between January 1 and December 31, 2014. Propensity score matching algorithm was used to balance differences in baseline characteristics among MIS and O-LR groups.

Results: A total of 3064 patients were included in the study. After propensity matching, the baseline characteristics for O-LR and MIS groups were comparable (minimum p value = 0.12). Incidence of superficial surgical site infections, intraoperative or postoperative blood transfusions, and pulmonary embolism was lower among patients in MIS group compared to O-LR (p < 0.02). Liver failure and biliary leakage were also less frequent among patients undergoing MIS (p < 0.01). Similarly, MIS was associated with a shorter length of hospital stay (LOS) compared to O-LR (p < 0.001). Of note, 30-day postoperative mortality and readmission were comparable between the two groups.

Conclusions: Patients undergoing MIS had a lower postoperative morbidity and shorter LOS compared with patients undergoing O-LR. MIS is safe and may be associated with improved short-term outcomes following hepatic surgery.

Keywords: Laparoscopic surgery; Liver surgery; Minimally invasive surgery; Robotic surgery.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Anastomotic Leak / epidemiology
  • Blood Transfusion / statistics & numerical data
  • Databases, Factual
  • Female
  • Hepatectomy / adverse effects
  • Hepatectomy / methods*
  • Humans
  • Incidence
  • Length of Stay
  • Liver Failure / epidemiology
  • Liver Neoplasms / etiology
  • Liver Neoplasms / surgery*
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures* / adverse effects
  • Postoperative Period
  • Propensity Score
  • Pulmonary Embolism / epidemiology*
  • Surgical Wound Infection / epidemiology*