Identification of a new potential mechanism responsible for severe bleeding in myeloma: immunoglobulins bind the heparin binding domain of antithrombin activating this endogenous anticoagulant

MeSH terms

• Aged
• Anticoagulants / chemistry
• Anticoagulants / metabolism
• Antithrombin III / chemistry
• Antithrombin III / metabolism*
• Binding Sites / physiology
• Factor VIIa / chemistry
• Factor VIIa / metabolism
• Female
• Hemorrhage / diagnosis
• Hemorrhage / etiology
• Hemorrhage / metabolism*
• Heparin / chemistry
• Heparin / metabolism*
• Humans
• Immunoglobulin G / chemistry
• Immunoglobulin G / metabolism*
• Multiple Myeloma / diagnosis
• Multiple Myeloma / metabolism*
• Protein Structure, Secondary
• Severity of Illness Index