Open-field exposure facilitates consummatory extinction

Neuroreport. 2016 Dec 7;27(17):1281-1286. doi: 10.1097/WNR.0000000000000693.

Abstract

During extinction, the organism learns that a conditioned stimulus or a conditioned response is no longer associated with an unconditioned stimulus, and as a consequence, a decrement in the response is presented. The exposure to novel situations (e.g. exploration of a novel open field) has been used widely to modulate (i.e. either enhance or deteriorate) learning and memory. The aim of the present study was to test whether open-field exposure could modulate consummatory extinction. The results indicated that open-field exposure accelerated the extinction response (i.e. experimental animals provided novelty exposure had lower consummatory behavior than control animals) when applied before - but not after - the first extinction trial, or when applied before the second extinction trial. The results suggest that environmental treatments such as novelty exposure provide a valuable, nonpharmacological alternative to potentially modulate extinction processes.

MeSH terms

  • Animals
  • Conditioning, Psychological / physiology*
  • Consummatory Behavior / physiology*
  • Exploratory Behavior / physiology*
  • Extinction, Psychological / physiology*
  • Fear / psychology*
  • Memory / physiology
  • Rats
  • Rats, Wistar
  • Time Factors