Concurrent STAT3, DNMT3A, and TET2 mutations in T-LGL leukemia with molecularly distinct clonal hematopoiesis of indeterminate potential

Am J Hematol. 2017 Jan;92(1):E6-E8. doi: 10.1002/ajh.24586. Epub 2016 Nov 18.

Authors

Philipp W Raess¹, Michael J Cascio¹, Guang Fan¹, Richard Press^{1

2}, Brian J Druker², Diana Brewer², Stephen E Spurgeon²

Affiliations

¹ Department of Pathology, Oregon Health and Science University, Portland, Oregon.
² Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon.

PMID: 27761930
DOI: 10.1002/ajh.24586

No abstract available

Publication types

Clinical Trial
Letter

MeSH terms

Aged
DNA (Cytosine-5-)-Methyltransferases / genetics*
DNA Methyltransferase 3A
DNA-Binding Proteins / genetics*
Dioxygenases
Hematopoiesis / genetics*
Humans
Leukemia, Large Granular Lymphocytic / genetics*
Male
Mutation*
Proto-Oncogene Proteins / genetics*
STAT3 Transcription Factor / genetics*

Substances

DNA-Binding Proteins
DNMT3A protein, human
Proto-Oncogene Proteins
STAT3 Transcription Factor
STAT3 protein, human
Dioxygenases
TET2 protein, human
DNA (Cytosine-5-)-Methyltransferases
DNA Methyltransferase 3A