The role of microRNAs in Anopheles biology-an emerging research field

Parasite Immunol. 2017 Feb;39(2). doi: 10.1111/pim.12405.

Abstract

In the last years, microRNAs (miRNAs) have been established as important post-transcriptional regulators of critical physiological processes in animals and plants. Here, we summarize what is known about miRNA biosynthesis, expression and function in the malaria vector mosquito Anopheles gambiae with a particular emphasis on the mosquito-parasite interactions. We discuss the important gaps in the current knowledge, including the potential of miRNA manipulation for future vector control strategies.

Keywords: Anopheles gambiae; Plasmodium; microRNA; vector competence.

Publication types

  • Review

MeSH terms

  • Animals
  • Anopheles / embryology
  • Anopheles / genetics*
  • Anopheles / parasitology*
  • Gene Expression Regulation / genetics*
  • Host-Parasite Interactions / genetics*
  • Life Cycle Stages
  • Malaria / parasitology
  • Malaria / transmission
  • MicroRNAs / biosynthesis
  • MicroRNAs / genetics*
  • Plasmodium / growth & development*

Substances

  • MicroRNAs