Vascular twin nevi

Am J Med Genet A. 2017 Jul;173(7):1919-1921. doi: 10.1002/ajmg.a.38117. Epub 2017 Apr 27.

Abstract

Vascular twin nevi (VTN) are characterized by the simultaneous dermatological manifestatiton of a telangiectatic naevus close to a nevus anemicus. Nevus anemicus (NA) is a vascular anomaly characterized by localized pale patches with normal melanine and melanocyte level. According to twin spotting phenomenon crossing-over in heterozygous somatic-cells during mitosis results in two different offspring homozygous cells. Consequent to this mechanism, two different vascular anomalies may occur at the same region. We present a patient with VTN and NA combination which we think serves as an example for a rare twin spotting phenomenon in the literature.

Keywords: nevus anemicus; telangiectatic nevi; twin spotting.