Role of Conventional Myelography in Diagnosis and Treatment of Degenerative Spine Disease in Low-Income Communities: Prospective Study

World Neurosurg. 2017 Aug:104:161-166. doi: 10.1016/j.wneu.2017.04.121. Epub 2017 Apr 27.

Abstract

Introduction: Chronic back pain is a common problem, and imaging is crucial for effective diagnosis and treatment. In low-resource settings conventional myelography is a cheap alternative to magnetic resonance imaging and computed tomography. This study was conducted to reexamine the diagnostic reliability, effectiveness for surgical decision making, and safety of conventional myelography.

Methods: The study was conducted at Tenwek Mission Hospital during June 2009 and March 2010. New patients who presented with features of radiculopathy and/or myelopathy were eligible. Standard anteroposterior views were taken; oblique views were obtained from patients with radiculopathy. Cervical and lumbosacral myelography was performed using iohexol contrast. Patients were observed for complications. Those with surgically remediable lesions underwent operation. Patients were monitored for symptom improvement and complication postoperatively.

Results: Fifty-one patients underwent diagnostic myelography and 39 of them (77.8%) were positive. Lesions at levels L4/5 were the most common, occurring in 23 patients (59%). Of those with cervical lesions, 11 of them (73.3%) had a positive myelography compared with 28 patients (77.8%) with lumbosacral lesions. Patients presenting with claudication were more likely to have a positive myelography, compared with those with other symptoms. There were 16 patients (41%) with partial spinal canal block, 6 patients (15.4%) with total block, and 17 patients (43.6%) with recess compression. Thirty-eight (38) patients had surgery, and recess decompression was the most common procedure (n = 24, 63.2%). Following surgery, symptoms due to degenerative spine disease improved in the majority of patients.

Conclusions: Conventional myelography is a reliable and safe diagnostic test. Appropriate and sound surgical decisions can be made following conventional myelography tests.

Keywords: Canal and recess stenosis; Claudication; Iohexal; Myelography; Myelopathy; Radiculopathy.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Developing Countries / statistics & numerical data*
  • Female
  • Humans
  • Intervertebral Disc Degeneration / diagnostic imaging*
  • Intervertebral Disc Degeneration / epidemiology
  • Intervertebral Disc Degeneration / surgery*
  • Male
  • Middle Aged
  • Myelography / statistics & numerical data*
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / prevention & control
  • Poverty / statistics & numerical data*
  • Prevalence
  • Prospective Studies
  • Risk Factors
  • Treatment Outcome
  • Uganda / epidemiology
  • Utilization Review