Recent advances in electrospun nanofibers for wound healing

Nanomedicine (Lond). 2017 Jun;12(11):1335-1352. doi: 10.2217/nnm-2017-0017. Epub 2017 May 18.

Abstract

Electrospun nanofibers represent a novel class of materials that show great potential in many biomedical applications including biosensing, regenerative medicine, tissue engineering, drug delivery and wound healing. In this work, we review recent advances in electrospun nanofibers for wound healing. This article begins with a brief introduction on the wound, and then discusses the unique features of electrospun nanofibers critical for wound healing. It further highlights recent studies that have used electrospun nanofibers for wound healing applications and devices, including sutures, multifunctional dressings, dermal substitutes, engineered epidermis and full-thickness skin regeneration. Finally, we finish with conclusions and future perspective in this field.

Keywords: electrospun nanofibers; local drug delivery; scaffold; skin regeneration; wound healing.

Publication types

  • Review

MeSH terms

  • Animals
  • Bandages
  • Drug Delivery Systems / methods*
  • Electrochemical Techniques / instrumentation
  • Electrochemical Techniques / methods
  • Equipment Design
  • Humans
  • Nanofibers / chemistry*
  • Nanofibers / therapeutic use*
  • Nanotechnology / instrumentation
  • Nanotechnology / methods
  • Regeneration / drug effects*
  • Regenerative Medicine / instrumentation
  • Regenerative Medicine / methods
  • Skin / drug effects
  • Skin Physiological Phenomena / drug effects*
  • Skin, Artificial
  • Sutures
  • Tissue Scaffolds / chemistry
  • Wound Healing / drug effects*