1 From the Division of General Medicine and the Center for Pharmaceutical Policy and Prescribing, University of Pittsburgh, and the Center for Health Equity Research and Promotion, Veterans Affairs Pittsburgh Healthcare System - both in Pittsburgh (W.F.G.): and the Program on Regulation, Therapeutics, and Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston (A.S.K.).