Innate mechanism of pollen- and cat dander-induced oxidative stress and DNA damage in the airways

J Allergy Clin Immunol. 2017 Nov;140(5):1436-1439.e5. doi: 10.1016/j.jaci.2017.04.044. Epub 2017 Jun 2.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 8-Hydroxy-2'-Deoxyguanosine
  • Adult
  • Allergens / immunology*
  • Animals
  • Antigens, Plant / immunology*
  • Bronchoalveolar Lavage Fluid / chemistry
  • Cats
  • DNA Damage*
  • Dander / immunology*
  • Deoxyguanosine / analogs & derivatives
  • Deoxyguanosine / analysis
  • Female
  • Glutathione Disulfide / analysis
  • HEK293 Cells
  • Humans
  • Immunity, Innate
  • Male
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Middle Aged
  • Nasal Mucosa / chemistry
  • Oxidative Stress*
  • Pollen / immunology*
  • Rhinitis, Allergic / immunology
  • Toll-Like Receptor 4 / physiology*

Substances

  • Allergens
  • Antigens, Plant
  • Tlr4 protein, mouse
  • Toll-Like Receptor 4
  • 8-Hydroxy-2'-Deoxyguanosine
  • Deoxyguanosine
  • Glutathione Disulfide