Cycling around Lysine Modifications

Surinder Kumar; David B Lombard

doi:10.1016/j.tibs.2017.05.006

Cycling around Lysine Modifications

Trends Biochem Sci. 2017 Jul;42(7):501-503. doi: 10.1016/j.tibs.2017.05.006. Epub 2017 Jun 6.

Authors

Surinder Kumar¹, David B Lombard²

Affiliations

¹ Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
² Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Institute of Gerontology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: davidlom@umich.edu.

Abstract

Recent studies have revealed the existence of a plethora of previously unknown protein acyl-lysine modifications, affecting the functions of targets involved in diverse cellular processes. A recent study from the Hirschey laboratory has provided new chemical insights into the mechanisms of protein acylation.

Keywords: HMGylation; MGcylation; MGylation; SIRT4; non-enzymatic acylation.

Publication types

Comment

MeSH terms

Acylation
Lysine*
Protein Processing, Post-Translational*

Substances

Lysine

Abstract

Publication types

MeSH terms

Substances

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