Semithiobambus[6]uril is a transmembrane anion transporter

Chem Commun (Camb). 2017 Jul 4;53(54):7557-7560. doi: 10.1039/c7cc04026a.

Abstract

Semithiobambus[6]uril is shown to be an efficient transmembrane anion transporter. Although all bambusuril analogs (having either O, S or N atoms in their portals) are excellent anion binders, only the sulfur analog is also an effective anion transporter capable of polarizing lipid membranes through selective anion uniport. This notable divergence reflects significant differences in the lipophilic character of the bambusuril analogs.

MeSH terms

  • Anions / chemistry
  • Anions / metabolism
  • Biological Transport
  • Chlorides / chemistry
  • Chlorides / metabolism
  • Hydrophobic and Hydrophilic Interactions
  • Imidazoles / chemistry
  • Imidazoles / metabolism*
  • Lipid Bilayers / chemistry
  • Lipid Bilayers / metabolism
  • Macrocyclic Compounds / chemistry
  • Macrocyclic Compounds / metabolism*
  • Molecular Structure

Substances

  • Anions
  • Chlorides
  • Imidazoles
  • Lipid Bilayers
  • Macrocyclic Compounds
  • bambus(6)uril