Gene-environment interaction between an IL4R variant and school endotoxin exposure contributes to asthma symptoms in inner-city children

J Allergy Clin Immunol. 2018 Feb;141(2):794-796.e3. doi: 10.1016/j.jaci.2017.08.023. Epub 2017 Sep 21.
No abstract available

Publication types

  • Clinical Trial
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asthma* / epidemiology
  • Asthma* / genetics
  • Asthma* / immunology
  • Child
  • Endotoxins / toxicity*
  • Environmental Exposure*
  • Female
  • Gene-Environment Interaction*
  • Humans
  • Interleukin-4 Receptor alpha Subunit / genetics
  • Interleukin-4 Receptor alpha Subunit / immunology
  • Male
  • Polymorphism, Genetic*
  • Prospective Studies
  • Schools*
  • Urban Population*

Substances

  • Endotoxins
  • IL4R protein, human
  • Interleukin-4 Receptor alpha Subunit