Problems encountered using temazepam syrup for sedation in infants

Eur J Pediatr. 1988 Jun;147(5):523-4. doi: 10.1007/BF00441981.

Abstract

Six infants with a history of wheezing were given temazepam syrup as sedation, to allow lung function tests to be performed. Despite doses ranging from 2.5 mg/kg-4.5 mg/kg only one infant remained a sleep for 1 h, the time taken for full lung function to be assessed. All other infants awoke within 15 min before test could be completed. Three infants developed hiccoughs and three were very irritable after awaking from sedation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Anxiety Agents / administration & dosage*
  • Humans
  • Hypnotics and Sedatives*
  • Infant
  • Respiratory Function Tests*
  • Sleep / drug effects
  • Temazepam / administration & dosage*
  • Temazepam / adverse effects

Substances

  • Anti-Anxiety Agents
  • Hypnotics and Sedatives
  • Temazepam