Radiopharmaceutical tracers for cardiac imaging

J Nucl Cardiol. 2018 Aug;25(4):1204-1236. doi: 10.1007/s12350-017-1131-5. Epub 2017 Dec 1.

Abstract

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Nuclear myocardial perfusion imaging with either single-photon emission computed tomography or positron emission tomography has been used extensively to perform diagnosis, monitor therapies, and predict cardiovascular events. Several radiopharmaceutical tracers have recently been developed to evaluate CVD by targeting myocardial perfusion, metabolism, innervation, and inflammation. This article reviews old and newer used in nuclear cardiac imaging.

Keywords: Cardiovascular disease; positron emission tomography; radiopharmaceutical; single-photon emission computed tomography.

MeSH terms

  • Apoptosis
  • Atherosclerosis / diagnostic imaging
  • Energy Metabolism
  • Fluorodeoxyglucose F18
  • Humans
  • Myocardial Perfusion Imaging / methods*
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography
  • Radiopharmaceuticals*
  • Sympathetic Nervous System / diagnostic imaging
  • Sympathetic Nervous System / physiopathology
  • Tomography, Emission-Computed, Single-Photon / methods*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18